Can "Lead Acetate" Be Absorbed Through Skin

LEAD ACETATE

MSDS Number: L2434 --- Effective Date: 08/15/99

i. Product Identification

Synonyms: Lead Acetate, Trihydrate; lead (Ii) acetate, trihydrate; acetic acid atomic number 82 (Two) salt, trihydrate; lead diacetate, trihydrate; Common salt of Saturn
CAS No.: 301-04-two
Molecular Weight: 379.33
Chemic Formula: Atomic number 82(C2H3O2)two . 3H2O
Production Codes:
J.T. Baker: 2271, 2273, 2279, 5165
Mallinckrodt: 4715, 5688

2. Composition/Information on Ingredients

        Ingredient                                CAS No         Per centum   Hazardous                                          ---------------------------------------   ------------   -------   ---------             Lead Acetate                              301-04-2       99 - 100%    Aye

3. Hazards Identification

Emergency Overview
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POISON! DANGER! MAY Be FATAL IF SWALLOWED, INHALED OR ABSORBED THROUGH Pare. Doubtable CANCER Run a risk. MAY CAUSE CANCER. Risk of cancer depends on level and elapsing of exposure. CAUSES IRRITATION TO SKIN, Eyes AND RESPIRATORY TRACT. NEUROTOXIN. AFFECTS THE Glue TISSUE, Cardinal NERVOUS Arrangement, KIDNEYS, BLOOD AND REPRODUCTIVE SYSTEM.
J.T. Bakery SAF-T-DATA^(tm) Ratings (Provided here for your convenience)
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Health Rating: iii - Astringent (Cancer Causing)
Flammability Rating: 0 - None
Reactivity Rating: 0 - None
Contact Rating: ane - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES
Storage Color Lawmaking: Bluish (Health)
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Potential Health Effects
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Inhalation:
Lead tin can be absorbed through the respiratory system. Local irritation of bronchia and lungs can occur and, in cases of astute exposure, symptoms such every bit metallic taste, chest and abdominal hurting, and increased lead blood levels may follow. See also Ingestion.
Ingestion:
Toxicant! The symptoms of lead poisoning include abdominal hurting and spasms, nausea, vomiting, headache. Acute poisoning tin can lead to muscle weakness, "atomic number 82 line" on the gums, metallic sense of taste, definite loss of appetite, insomnia, dizziness, high lead levels in blood and urine with shock, coma and death in extreme cases.
Skin Contact:
Lead and lead compounds may be absorbed through the pare on prolonged exposure; the symptoms of lead poisoning described for ingestion exposure may occur. Contact over short periods may cause local irritation, redness and hurting.
Heart Contact:
Absorption can occur through center tissues but the more common hazards are local irritation or chafe.
Chronic Exposure:
Atomic number 82 is a cumulative poison and exposure even to small amounts can raise the body's content to toxic levels. The symptoms of chronic exposure are similar those of ingestion poisoning; restlessness, irritability, visual disturbances, hypertension and gray facial color may also be noted.
Aggravation of Pre-existing Weather condition:
Persons with pre-existing kidney, nerve or circulatory disorders or with skin or eye problems may exist more susceptible to the effects of this substance.

iv. Offset Assistance Measures

Inhalation:
Remove to fresh air. If non animate, requite bogus respiration. If animate is difficult, give oxygen. Become medical attention.
Ingestion:
Induce vomiting immediately every bit directed by medical personnel. Never give anything past mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush pare with plenty of soap and h2o for at least fifteen minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes earlier reuse.
Heart Contact:
Immediately flush eyes with enough of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Go medical attending immediately.

v. Fire Fighting Measures

Burn:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion take chances.
Burn Extinguishing Media:
Use any means suitable for extinguishing surrounding fire. Practise not allow water runoff to enter sewers or waterways.
Special Data:
In the effect of a fire, wear full protective article of clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure need or other positive force per unit area way. Atomic number 82 acetate can produce acetic acid, carbon monoxide, and toxic fumes of lead oxide in burn down situations.

6. Adventitious Release Measures

Ventilate area of leak or spill. Habiliment appropriate personal protective equipment as specified in Section viii. Spills: Sweep upwardly and containerize for reclamation or disposal. Vacuuming or wet sweeping may exist used to avert dust dispersal. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in backlog of reportable quantities. The toll gratis number for the United states Declension Guard National Response Eye is (800) 424-8802.

seven. Treatment and Storage

Keep in a tightly closed container, stored in a cool, dry out, ventilated area. Protect against physical damage. Isolate from incompatible substances. Areas in which exposure to atomic number 82 metal or lead compounds may occur should be identified by signs or appropriate means, and access to the surface area should exist express to authorized persons. Containers of this material may be chancy when empty since they retain product residues (dust, solids); notice all warnings and precautions listed for the product.

viii. Exposure Controls/Personal Protection

Airborne Exposure Limits:
For lead, metal and inorganic dusts and fumes, as Pb:
-OSHA Permissible Exposure Limit (PEL): 0.05 mg/m3 (TWA)
For lead, elemental and inorganic compounds, as Pb:
-ACGIH Threshold Limit Value (TLV): 0.05 mg/m3 (TWA), A3 animate being carcinogen
ACGIH Biological Exposure Indices (BEI): 30 ug/100ml, notation B (run into actual Indices for more information).
For lead, inorganic:
-NIOSH Recommended Exposure Limit (REL): 0.i mg/m3 (TWA)
Ventilation Organisation:
A organization of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is mostly preferred considering it can command the emissions of the contaminant at its source, preventing dispersion of information technology into the general work surface area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, almost recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face high efficiency dust/mist respirator may exist worn for up to ten times the exposure limit or the maximum use concentration specified by the advisable regulatory agency or respirator supplier, whichever is lowest. A total-face piece high efficiency dust/mist respirator may exist worn up to 50 times the exposure limit, or the maximum utilise concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure level, air-supplied respirator. WARNING: Air-purifying respirators practise non protect workers in oxygen-deficient atmospheres.
Skin Protection:
Habiliment impervious protective wearable, including boots, gloves, lab coat, apron or coveralls, as appropriate, to forestall skin contact.
Centre Protection:
Use chemic safe goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain centre wash fountain and quick-drench facilities in piece of work area.
Other Command Measures:
Eating, drinking, and smoking should not be permitted in areas where solids or liquids containing pb compounds are handled, processed, or stored. Come across OSHA substance-specific standard for more than information on personal protective equipment, engineering and piece of work practice controls, medical surveillance, record keeping, and reporting requirements. (29 CFR 1910.1025).

9. Physical and Chemical Properties

Advent:
White crystalline granules.
Odor:
Slight acerb acid odor.
Solubility:
60 gm in 100 gm water.
Specific Gravity:
two.55
pH:
5.v-6.5
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
ca. 100C (ca. 212F) Decomposes.
Melting Point:
75C (167F)
Vapor Density (Air=1):
No information constitute.
Vapor Pressure (mm Hg):
No information constitute.
Evaporation Rate (BuAc=1):
No information constitute.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of apply and storage. Readily absorbs CO2 from the air.
Hazardous Decomposition Products:
Toxic fumes of lead or lead oxide and carbon monoxide may be released when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Bromates, phenol, chloral hydrate, sulfides, hydrogen peroxide, resorcinol, salicylic acid, sulfites, vegetable infusions, alkalis, tannin, phosphates, citrates, chlorides, carbonates, tartrates and acids.
Weather to Avoid:
Estrus, flames, ignition sources and incompatibles.

eleven. Toxicological Information

Toxicological Data:
LD50 Oral Rat: 4665 mg/kg (trihydrate form). Investigated every bit a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
Lead and other smelter emissions are human reproductive hazards. (Chemic Council on Environmental Quality; Chemical Hazards to Human Reproduction, 1981).
Carcinogenicity:
EPA / IRIS classification: Group B2 - Probable human carcinogen, sufficient animal evidence.

        --------\Cancer Lists\------------------------------------------------------                                          ---NTP Carcinogen---   Ingredient                             Known    Predictable    IARC Category   ------------------------------------   -----    -----------    -------------   Lead Acetate (301-04-ii)                 No          Yes             three

12. Ecological Data

Environmental Fate:
When released into the soil, this material is non expected to leach into groundwater. This material may bioaccumulate to some extent.
Environmental Toxicity:
No data constitute.

13. Disposal Considerations

Whatsoever cannot be saved for recovery or recycling should exist handled as chancy waste matter and sent to a RCRA canonical waste facility. Processing, use or contagion of this product may change the waste management options. Country and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

fourteen. Transport Information

Domestic (Land, D.O.T.)
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Proper Aircraft Proper name: RQ, LEAD ACETATE
Take a chance Course: 6.1
UN/NA: UN1616
Packing Group: 3
Information reported for product/size: 400LB
International (Water, I.K.O.)
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Proper Shipping Proper noun: Pb ACETATE
Hazard Class: 6.1
Un/NA: UN1616
Packing Group: 3
Information reported for product/size: 400LB

fifteen. Regulatory Information

        --------\Chemical Inventory Status - Part i\---------------------------------   Ingredient                                       TSCA  EC   Japan  Commonwealth of australia   -----------------------------------------------  ----  ---  -----  ---------   Pb Acetate (301-04-ii)                           Yes  Yep   Yes      Aye                                           --------\Chemical Inventory Status - Office ii\---------------------------------                                                           --Canada--   Ingredient                                       Korea  DSL   NDSL  Phil.   -----------------------------------------------  -----  ---   ----  -----   Lead Acetate (301-04-two)                           Yes   Yep   No     Aye                                  --------\Federal, State & International Regulations - Part ane\----------------                                              -SARA 302-    ------SARA 313------   Ingredient                                 RQ    TPQ     List  Chemical Catg.   -----------------------------------------  ---   -----   ----  --------------   Atomic number 82 Acetate (301-04-2)                    No    No      No    Atomic number 82 compoun     --------\Federal, State & International Regulations - Part ii\----------------                                                         -RCRA-    -TSCA-   Ingredient                                 CERCLA     261.33     8(d)    -----------------------------------------  ------     ------    ------   Atomic number 82 Acetate (301-04-2)                    10         U144       No                        Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No SARA 311/312:  Acute: Yeah      Chronic: Yes  Fire: No  Pressure: No Reactivity: No          (Mixture / Solid)

Alert:
THIS PRODUCT CONTAINS CHEMICALS KNOWN TO THE Land OF CALIFORNIA TO CAUSE CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE Impairment.
Australian Hazchem Code: 2Z
Poisonous substance Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Wellness: iii Flammability: ane Reactivity: 0
Label Adventure Warning:
POISON! DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR Captivated THROUGH SKIN. Suspect CANCER Take a chance. MAY CAUSE CANCER. Chance of cancer depends on level and duration of exposure. CAUSES IRRITATION TO SKIN, Eyes AND RESPIRATORY TRACT. NEUROTOXIN. AFFECTS THE Glue TISSUE, Primal NERVOUS SYSTEM, KIDNEYS, Blood AND REPRODUCTIVE Organisation.
Label Precautions:
Practice non breathe dust.
Exercise not make it eyes, on pare, or on clothing.
Keep container closed.
Apply simply with adequate ventilation.
Wash thoroughly later treatment.
Label First Help:
If swallowed, induce airsickness immediately equally directed by medical personnel. Never give annihilation by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If animate is difficult, give oxygen. In instance of contact, immediately flush eyes or skin with plenty of h2o for at least xv minutes. Remove contaminated vesture and shoes. Wash clothing before reuse. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(due south) changed since terminal revision of document include: i.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation equally to its comprehensiveness or accuracy. This certificate is intended only every bit a guide to the advisable precautionary handling of the cloth by a properly trained person using this product. Individuals receiving the data must exercise their independent judgment in determining its ceremoniousness for a particular purpose. MALLINCKRODT Bakery, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION Whatever WARRANTIES OF MERCHANTABILITY, Fettle FOR A PARTICULAR PURPOSE WITH RESPECT TO THE Data SET FORTH HEREIN OR THE Product TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT Baker, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM Utilise OF OR RELIANCE UPON THIS Information.
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Prepared past: Strategic Services Division
Telephone Number: (314) 539-1600 (U.S.A.)